Om Swami
What can I do when I am helpless in the face of a loss or someone's pain?
Do what help you can, then pray
When you are helpless, do all the possible help and then pray. You cannot pray to do away with someone's pain, because pain is a state of mind. Disease, unmet desires or loss in business should not be considered wrong and should not cause you pain.
Besides all the possible help you can give, there is only one thing you can do, and that is pray.